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INSTYTUT CHEMII ORGANICZNEJ

MONDAY

 

10:30 - 12:00

Registration

12:00 – 12:15

Welcome

CHAIR

Christian Ducho

12:15 – 13:00

Epitope mapping as a probe for tracking autoimmunological diseases

Beata Kolesińska, Lodz University of Technology, Poland

13:00 – 13:25

Assembly and analysis of HSV using noncanonical amino acids, click-chemistry and fluorescent capture reagents

Remigiusz Serwa, Imperial College of London, UK

13:25 – 13:40

Design and synthesis of novel probes for plant proteins

Daniel Krahn, Renier van der Hoorn, University of Oxford, U.K.

 

 

13:40 – 14:55

Lunch

 

 

CHAIR

Remigiusz Serwa

14:55 – 15:20

Highly Efficient Bioorthogonal Catalysis Reaction with Improved Biocompatibility for Click Chemistry

Ozlem Dilek, Istanbul Kemerburgaz Universitesi

15:20 – 15:45

Substrate specificity profiling and its application in inhibitor and probe design

Steven Verhelst, University of Leuven, Belgium

15:45 – 16:00

Unnatural amino acids in design of proteases probes

Katarzyna Groborz, Marcin Drąg, Wrocław University of Technology, Poland

16:00 – 16:15

Hyper-reactive Cys profiling in plants

Kyoko Morimoto, Renier van der Hoorn, University of Oxford, U.K.

 

 

16:15 – 16:30

Coffee break

 

 

16:30 – 17:30

Future initiatives: for PIs only

17:30 -

Free evening

 

TUESDAY

 

CHAIR

Ozlem Dilek

9:10 – 9:35

Chemoproteomics-enabled discovery of cysteine-reactive inhibitors

Alexander Adibekian, University of Geneva, Switzerland

9:35 – 10:00

P2Y purinoceptors mediate phosphorothioate nucleotides-induced changes in intracellular calcium as well as long-term effects

Maria Koziołkiewicz, Edyta Węgłowska, Marcin Szustak, Edyta Gendaszewska-Darmach, Lodz University of Technology, Poland

10:00 – 10:15

Development of reagents for MS-based chemical proteomics using a modular approach

Jacob Hauser, Robin Bon, University of Leeds, UK

10:15-10:30

Synthesis of Ahp-cyclodepsipeptides as protease inhibitors

Steffen Köcher, Markus Kaiser, University of Duisburg-Essen, Germany

 

 

10:30 – 11:00

Coffee break

 

 

CHAIR

Artur Mucha

11:00 – 11:45

Development of inhibitors of the p53-MDM2/MDMX interaction

Tad Holak, Aleksandra Twarda, Jagiellonian University, Poland

11:45 – 12:10

Click chemistry in construction of electrochemically active probes

Agnieszka Olejniczak, Institute of Medical Biology of PAS, Poland

12:10 – 12:35

Chemical and Genetic Interrogation of Novel Antimalarial Targets

Edgar Deu, The Francis Crick Institute, UK

12:35 – 12:50

Phosphorus analogues of isothiocyanates – synthesis, biological activity and their application as potential fluorescent probes

Łukasz Janczewski, Tadeusz Gajda, Lodz University of Technology, Poland

 

 

12:50 – 14:05

Lunch

 

 

CHAIR

Steven Verhelst

14:05 – 14:30

Proteomics enquiry of adaptation to proteasome inhibitors in leukemia

Bogdan Florea, University of Leiden, Netherlands

14:30 – 14:55

Covalent inhibitors of bacterial ureases

Łukasz Berlicki, Wrocław University of Technology, Poland

14:55 – 15:20

Target identification for bioactive small molecules

Markus Kaiser, University of Duisburg-Essen, Germany

15:20 – 15:35

Design and synthesis of potential phosphonocarboxylate inhibitors and probes for RabGGTase

Łukasz Joachimiak, Michał Jakubczyk, Katarzyna Błażewska, Lodz University of Technology, Poland

15:35 – 15:40

Closing remarks

   

15:40 – 16:00

Coffee break

16:00 -

Exploring Łódź

19:00

Final dinner at Gronowalski Restaurant

 

NASZE SUKCESY

KOMUNIKATY

MIĘDZYNARODOWE PROGRAMY

WSPÓŁPRACUJEMY